Los académicos del Departamento de Reumatología tienen presencia nacional e internacional en la especialidad lo que se traduce en la publicación de artículos, participación en congresos locales y en el extranjero con la presentación de trabajos o conferencias. En esta sección ponemos a disposición de nuestros visitantes parte de este material.

Por Formato

Libros
Textos extensos, tratados en forma exhaustiva, escritos para formato impreso, luego traspasados al web.
  1. Capítulo "Artritis reumatoidea. Manifestaciones extraarticulares" en Tratado Reumatología (ARAN Ediciones, 1998, pags 461-476). Dres Sergio Jacobelli y Santiago Rivero

  2. Capítulo "Lupus eritematoso Sistémico" en Tratado Iberoamericano de Reumatología (Global Solution System, 1999, pags 273-277). Dres. Sergio Jacobelli y Santiago Rivero.
  3. Bravo M. Capítulo “Exocitic pathway check points for functional potassium channels in the plasma membrane”, en Libro : Pumas, transporters and ion channels. Studies on their structure, function and cell biology.
  4. Massardo L. Capítulo “Etanercept”, en “ Artritis Reumatoide: Bases moleculares, Clínicas y terapéuticas”, 2006.
  5. Massardo L, Gutiérrez MA. Capítulo “La artritis reumatoide como una prioridad de salud pública en Chile”, en “Retos para el diagnóstico y tratamiento de la Artritis Reumatoide en América Latina”, 2006
  6. Capítulo " Manifestaciones Articulares" en Tratado Hispanoamericano de Reumatología (Editorial Nomos S.A. 2006. 465-479). Dres. Sergio Jacobelli y Miguel Gutierrez.
  7. Capitulo “ Espondilitis Anquilosante”, en Espondiloartropatías (Panamericana S.A, 2007, 198-214). Dres. Miguel Gutierrez y Francisco Silva.
Temas online
Textos extensos, tratados en forma exhaustiva, desarrollados originalmente para el web
  1. Apuntes de Reumatología, para alumnos de pregrado
    Editor: Dra Loreto Massardo

  2. Atlas de Reumatología Editores: Dres Sergio Jacobelli y Marcela Cisternas

Papers
Artículos en formato de comunicación científica, publicados entre los años 2006-2010, muchos de los cuales se encuentran indexados en http://www.ncbi.nlm.nih.gov/pubmed

Año 2006

Merino G., Varas G., Díaz G., Gutiérrez M., Massardo L., Pacheco D., Villarroel F., Cuchacovich M. Eficacia del infliximab en pacientes con síndrome de Behcet portadores de úveo-retinitis grave. Rev Med Chile 2006; 134:875-882.

Cuchacovich M., Soto L., Edwardes M., Gutiérrez M., Llanos C., Pacheco D., Sabugo F., Alamo M., Fuentealba C., Villanueva L., Gatica H., Schiattino I., Salazar L., Catalan D., Valenzuela O., Salazar-Onfray F., Aguillón J. Tumour necrosis factor (TNF)α -308 G/G promoter polymorphism and TNFα levels correlate with a better response to adalimumab in patients with rheumatoid arthritis. Scand J Rheumatol 2006; 35:435-440.

Iruretagoyena M., Sepúlveda S., Lezana P., Hermoso M., Bronfman M., Gutiérrez M., Jacobelli S., Kalergis A. Inhibition of nuclear factor KB enhances the capacity of immature dendritic cells to induce antigen-specific tolerante in experimental autoinmune encephalomyelitis. J Phar Exp Therapeutics 2006; 318(1):59-67

Iruretagoyena M., Wiesendanger M., Kalergis A. The dendritic cell-T cell synapse as a determinant of autoimmune pathogenesis. Curr Pharm Des 2006;12(2):131-47

Alvarez-Lobos M., Hunter B., Cofre C., Benitez C., Talesnik E., Oyarzo M., Arostegui J.I., Yagüe. TRAPS, un síndrome autoinflamatorio casos clínicos. Rev Med Chile 2006;134:1558-1561 By the Latin American Rheumatology Associations of the Pan-American League of Associations for Rheumatology (PANLAR) and the Grupo Latinoamericano de Estudio de Artritis Reumatoide (GLADAR). First Latin American position paper of the pharmacological treatment of rheumatoid arthritis. Rheumatology 2006;45:ii7-ii22

Talesnik E., Hoyos R. Nueva nomenclatura de las enfermedades alérgicas. Su aplicación a la práctica pediátrica. Rev Med Chile 2006;77(3):239-246

Majerson D., Talesnik E., Harris P. Entendiendo la relación entre la infección por Helicobacter pylori y enfermedades alérgicas en niños y adultos. Gastr Latinoam 2006; 17(3):329-337

Karassa F., Afeltra A., Ambrozic A., Chang D., De Keyser F., Doria A., Galeazzi M., Hirohata S., Hoffman I., Inanc M., Massardo L., Mathieu A., Mok Ch., Morozzi G., Sanna G., Spindler A., Tzioufas A., Yoshio T., Ioannidis J. Accuracy of Anti-Ribosomal P Protein antibody testing for the diagnosis of neuropsychiatric systemic lupus erythematosus. Arth Rheum 2006; 54(1):312-324

Pardo E., Cárcamo C., Massardo L., Mezzano L., Iacobelli S., González A., Soza A. Autoanticuerpos anti-galectina-8 en pacientes con lupus eritematoso sistémico. Rev Med Chile 2006;134:159-166

Cárcamo C., Pardo E., Oyanadel C., Bravo M., Bull P., Cáceres M., Martínez J., Massardo L., Iacobelli S., González A., Soza A. Galectin-8 binds specific β1 integrins and induces polarized spreading highlighted by asymmetric lamellipodia in Jurkat T cells. Exp Cell Res 2006; 312:374-396

Pereira J., Alfaro G., Goycoolea M., Quiroga T., Ocqueteau M., Massardo L., Pérez C., Sáez Cl, Panes O., Matus V., Mezzano D. Cirgulating platelet-derived microparticles in systemic lupus erythematosus. Throm Haemost 2006;95: 94-9

Año 2007

Reyes M.L., Hernández M.I., King A., Vinet A.M., Vogel A., Lagomarsino E., Mericq M.V., Méndez C., Gederline A., Talesnik E. Corticosteroid-induced osteoporosis in children: outcome after two year follow up, risk factors, densitometric predictive cut off values for vertebral fractures. Clin Exp Rheum 2007; 25:329-335

Año 2008

Ramírez L.A., Uribe O., Osio O., Romero H., Cardiel M.H., Wojdyla D., Pons-Estel B., ando n behalf of the Grupo Latinoamericano de estudio del Lupus (GADEL, Massardo L.) Childhood systemic lupus erythematosus in latin America. The GLADEL experience in 230 children. Lupus 2008;17:596-604

Soriano E., Galarzo C., Cardiel M., Pons-Estel B., Massardo L., Caballero C., Achurra A., Barile L., Chavez J., Díaz J., Esteve M., Guibert M., Irazoque F., Keiserman M., Lomonte A., Mota L., Pineda C., Alrcón G., on behalf of GLADAR (Grupo Latino Americano de Estudio de Artritis Reumatoide). Use of rituximab for the treatment of rheumatoid arthritis: the Latin American cotest. Rheumatology 2008;47:1097-1099

Massardo L., Artritis reumatoide temprana. Rev Med Chile 2008;136:1468-1475

Año 2009

Massardo L, Metz C, Pardo E, Mezzano V, Babul M, Jarpa E, Guzmán A, André S, Kaltner H, Gabius H, Jacobelli S, González A, *Soza A. (2009). Autoantibodies against galectin-8: their specificity, association with lymphopenia in systemic lupus erythematosus and detection in rheumatoid arthritis and acute inflammation. Lupus. 2009;18(6):539-46

Norambuena A, Metz C, Vicuña L, Silva A, Pardo E, Oyanadel C, Massardo L, González A, *Soza A. Galectin-8 Induces Apoptosis in Jurkat T Cells by Phosphatidic Acid-mediated ERK1/2 Activation Supported by Protein Kinase A Down-regulation. J Biol Chem, 2009; 284(19):12670-9

Donoso M., Cancino J., Lee J., van Kerhof P., Retamal C., Bu G., González A., Cáceres A., Marzolo M.P. Polarized traffic of LRP1 involves AP1B and SNX17 operating upon Y-dependent sorting motifs in different pathways. Mol Biol Cell 2009;20(1):481-497

Toro, A., Araya C., Córdova G., Arredondo C., Cárdenas H., Moreno R., Venegas A., Koenig C., Cancino J.,

Gonzalez A., and Santos M. Pex3p-dependent peroxisomal biogenesis initiates in the endoplasmic reticulum of human fibroblasts. J Cell Biochem 2009;107(6): 1083-1096 Gonzalez A and Rodriguez-Boulan Clathrin and AP1B: Key roles in basolateral trafficking and transendosomal routes. E. FEBS Letters. Special Issue “The Golgi Complex”, 2009;583(23): 3784-3795

Loreto Massardo, et al. Management of patients with RA in Latin America. A consensus position paper from PANLAR and GLADAR. A report from PANLAR AND GLADAR Consensus Meeting on Education and the Use of DMARDs and Biologics in Latin American Countries. J Clin Rheumatol. 2009 Jun; 15(4):203-10. Review. PMID: 19502907

Carreño LJ, Pacheco R, Gutierrez MA, Jacobelli S, Kalergis AM.Disease activity in systemic lupus erythematosus is associated with an altered expression of low-affinity Fc gamma receptors and costimulatory molecules on dendritic cells. Immunology. 2009 Nov; 128(3):334-41.

Jurado M, Durán J, Martínez A, Castellón JM, Gutiérrez MA. Infarto agudo al miocardio en un hombre joven sin ateromatosis coronaria, como forma de presentación de síndrome antifosfolípido primario. Caso clínico. Rev. méd. Chile, Nov 2009, 137; 11: 1478-1481. ISSN 0034-9887

Silva F, Specks U, Sethi S, Irazabal MV, Fervenza FC. Successful pregnancy and delivery of a healthy newborn despite transplacental transfer of antimyeloperoxidase antibodies from a mother with microscopic polyangiitis. Am J Kidney Dis. 2009 Sep; 54(3):542-5. Epub 2009 Apr 23.

Jorge Yáñez, Marcela Cisternas, Velia Saldías,Fernando Saldías Dermatomiositis refractaria asociada a neumonía en organización tratada con rituximab. Reporte de un caso P1. Rev Méd Chile 2009; 137: 88-93

Guillermo Pons-Estel, Luis A. Gonzalez, Jie Zhang, Paula I. Burgos, John D. Reveille, Luis M. Vila and Graciela Alarcon. "Predictors of cardiovascular damage in patients with systemic lupus erythematosus: data from LUMINA (LXVIII), a multiethnic US cohort" Rheumatology (Oxford) 2009,48(7):817-822.PMID: 19454606

Burgos PI, Alarcón GS, McGwin G Jr, Crews KQ, Reveille JD, Vilá LM. "Disease activity and damage are not associated with increased levels of fatigue in systemic lupus erythematosus patients from a multiethnic cohort: LXVII" Arthritis Rheum. 2009;61(9):1179-1186.PMID: 19714612

Burgos PI, Perkins EL, Pons-Estel GJ, Kendrick SA, Liu JM, Kendrick WT, Cook WJ, Julian BA, Alarcón GS, Kew CE 2nd. "Risk factors and impact of recurrent lupus nephritis in patients with systemic lupus erythematosus undergoing renal transplantation: Data from a single US institution" Arthritis Rheum. 2009; 27; 60(9):2757-2766. PMID: 19714623

BA Pons-Estel, J Sánchez-Guerrero, J Romero-Díaz, A Iglesias-Gamarra, E Bonfa, EF Borba, SK Shinjo,S Bernatsky, A Clarke, MAGarcía, JCMarcos, ADuarte, GA Berbotto,, LJ Catoggio, O Neira, PI Burgos et al. “Validation of the Spanish, Portuguese and French versions of the Lupus Damage Index questionnaire: data from North and South America, Spain and Portugal” Lupus. 2009; 18 (12):1033-52. PMID: 197623

Burgos PI, Vilá LM, Reveille JD, Alarcón GS. “Peripheral vascular damage in systemic lupus erythematosus: data from LUMINA, a large multi-ethnic U.S. cohort (LXIX)”. Lupus 2009; 48 (11):1392-7. PMID: 19850658.

Uribe AG, Romero-Díaz J, Apte M, Fernández M, Burgos PI, Reveille JD, Sánchez-Guerrero J, Alarcón GS. "Impact of immigration on the clinical expression of systemic lupus erythematosus: a comparative study of Hispanic patients residing in the USA and Mexico". Rheumatology (Oxford) 2009; Vol (11): 1392-1397. PMID: 19717548.

Burgos PI, Alarcón GS. “Thrombosis in Systemic Lupus Erythematosus: Risk and Protection”. Expert Review of Cardiovascular Therapy 2009; 7(12):1541-9. PMID: 19954316

Paula I. Burgos, MD 1, Maria I. Danila, MD, MSc, James M. Kelley, PhD, Laura B. Hughes, MD, MSPH, and S. Louis Bridges, Jr. MD, PhD1, 2 “Understanding Personalized Medicine in Rheumatoid Arthritis: A Clinician’s Guide to the Future”..Therapeutic Advances in Musculoskeletal Disease 2009, 1(2): 97-105.

Kalergis AM, Iruretagoyena MI, Barrientos MJ, González PA, Herrada AA, Leiva ED, Gutiérrez MA, Riedel CA, Bueno SM, Jacobelli SH. Modulation of nuclear factor-kappaB activity can influence the susceptibility to systemic lupus erythematosus. Immunology, 2009 Sep;128(1 Suppl):e306-14. Epub 2008 Nov 7.

Carreño LJ, Pacheco R, Gutierrez MA, Jacobelli S, Kalergis AM. Disease activity in systemic lupus erythematosus is associated with an altered expression of low-affinity Fc gamma receptors and costimulatory molecules on dendritic cells. Immunology. 2009 Nov; 128(3):334-41.

Año 2010

Norambuena A, Metz C, Jung J, Silva A, Otero C, Cancino J, Retamal C, Valenzuela JC, Soza A and González A. Phosphatidic Acid Induces Ligand-independent EGFR Endocytic Traffic Through PDE4 Activation. Mol Biol Cell 2010; 21(16):2916-29

Jarpa E., Babul M., Calderón J., González M., Martínez M.E., Bravo-Zehnder M., Jacobelli S., González A., and Massardo L. “Common Mental Disorders and Psychological Distress in Systemic Lupus Erythematosus are not associated with Disease Activity”. LUPUS in press. 2010

Norambuena A, Palma F, Poblete MI, Donoso MV, Pardo E, Gonzalez A, Huidobro-Toro JP. UTP controls cell surface distribution and vasomotor activity of the human P2Y2 receptor through an epidermal growth factor receptor-transregulated mechanism. J Biol Chem. 2010; 285(5):2940-50.

Shinjo SK, Bonfá E, Wojdyla D, Borba EF, Massardo L, et al . Antimalarial treatment may have a time-dependent effect on lupus survival: data from a multinational Latin American inception cohort. Arthritis Rheum. 2010 Mar; 62(3):855-62.PMID: 20131238

JC Lizarazo-Barrera, S Jacobelli, P Mellado, S Gonzalez, L Massardo. Trombosis de senos venosos encefalicos como posible primera manifestación de enfermedad de Behcet: caso clinico. Rev Med Chile. 138:737-742

Duran J., Jurado M., Jacboelli S., Eymin G., Castiglioni E., Valenzuela R., Gutiérrez MA. Pseudotumor cerebri como una manifestación excepcional de la enfermedad de Behçet: Caso clínico. Rev Med Chile 2010; 138: 334-337

Silva F, Hummel AM, Jenne DE, Specks U. Discrimination and variable impact of ANCA binding to different surface epitopes on proteinase 3, the Wegener's autoantigen. J Autoimmun. 2010 Aug 30. [Epub ahead of print]

Silva F, Specks U, Kalra S, Hogan MC, Leung N, Sethi S, Fervenza FC. Mycophenolate mofetil for induction and maintenance of remission in microscopic polyangiitis with mild to moderate renal involvement--a prospective, open-label pilot trial. Clin J Am Soc Nephrol. 2010 Mar; 5(3):445-53. Epub 2010 Jan 21.

S. Louis Bridges, Jr., Zenoria L. Causey, Paula I. Burgos, B. Quynh N. Huynh, et al. "Radiographic Severity of Rheumatoid Arthritis in African-Americans: Results from the CLEAR Registry". Arthritis Care Res (Hoboken). 2010 May; 62(5):624-31.

“Reply” to “Global versus organ-specific outcome measures in systemic lupus erythematosus: Comment on the articles by Furie et al, Nikpour et al, Wallace et al, Burgos et al, and Ramos-Casals et al (p 580-581)” Graciela S. Alarcón MD, MPH, Gerald McGwin Jr. MS, PhD, Paula I. Burgos MD.

Burgos PI, Causey ZL, Tamhane A, Kelley JM, Brown EE, Hughes LB, Danila MI, van Everdingen A, Conn DL, Jonas BL, Callahan LF, Smith EA, Brasington R, Moreland LW, van der Heijde DM, Alarcon GS, Bridges SL Jr. “Association of IL4R single nucleotide polymorphisms with rheumatoid nodules in African Americans with rheumatoid arthritis". Arthritis Res Ther. 2010 May 5; 12(3):R75. [Epub ahead of print]

Burgos PI, McGwin G Jr, Reveille JD, Vilá LM, Alarcón GS. "Factors predictive of thrombotic events in LUMINA, a multi-ethnic cohort of SLE patients (LXXII)" Rheumatology (Oxford). 2010 May 23. [Epub ahead of print] PMID: 20498010 [PubMed - as supplied by publisher]

Shinjo SK, Bonfá E, Wojdyla D, Borba EF, Ramirez LA, Scherbarth HR, Brenol JC, Chacón-Diaz R, Neira OJ, Berbotto GA, De La Torre IG, Acevedo-Vázquez EM, Massardo L, Barile-Fabris LA, Caeiro F, Silveira LH, Sato EI, Buliubasich S, Alarcón GS, Pons-Estel BA; Grupo Latino Americano de Estudio del Lupus Eritematoso (Gladel). Antimalarial treatment may have a time-dependent effect on lupus survival: data from a multinational Latin American inception cohort. Arthritis Rheum. 2010 Mar; 62(3):855-62.

Burgos PI, McGwin G Jr, Reveille JD, Vilá LM, Brown EE, Alarcon GS. Is familial lupus different from sporadic lupus? Data from LUMINA (LXXIII), a multiethnic US cohort. Lupus. 2010 Oct; 19(11):1331-6. Epub 2010 Aug 9.

Burgos PI, McGwin G Jr, Pons-Estel GJ, Reveille JD, Alarcón GS, Vilá LM. US patients of Hispanic and African ancestry develop lupus nephritis early in the disease course: data from LUMINA, a multiethnic US cohort (LUMINA LXXIV). Ann Rheum Dis. 2010 Jul 13. [Epub ahead of print]

Burgos PI, Alarcón GS. Preventive health services for systemic lupus erythematosus patients: whose job is it?. Arthritis Res Ther. 2010; 12(3):R84. Arthritis Res Ther. 2010; 12(3):124. Epub 2010 Jun 17.

Lizarazo-Barrera JC, Jacobelli S, Mellado P, González S, Massardo L. Extensive cerebral vein thrombosis as first manifestation of Behçet's disease. Report of one case. Rev Med Chil. 2010 Jun; 138(6):746-51.